Practical Neurology

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Practical Neurology 2006;6:111-116; doi:10.1136/jnnp.2006.089003
Copyright © 2006 by the BMJ Publishing Group Ltd.

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Neurological rarity

POEMS syndrome

Rachel Caswell1, Thomas Warner1, Atul Mehta2, Lionel Ginsberg1

1 Department of Neurology, Royal Free Hospital, London, UK
2 Department of Haematology, Royal Free Hospital, London, UK

Correspondence to:
Correspondence:
Dr L Ginsberg, Department of Neurology, Royal Free Hospital, Pond Street, London, UK;
Lionel.Ginsberg@royalfree.nhs.uk

The first 150 words of the full text of this article appear below.

A man in his forties was admitted to hospital with lower limb weakness and numbness. Symptoms had started four weeks earlier with pins and needles in the soles. Weakness and numbness had then ascended symmetrically, also affecting both hands. At the time of admission he was unable to walk but swallowing was normal and there were no respiratory symptoms. He had recovered from an upper respiratory tract infection three weeks before the onset of his neurological symptoms. There was also a recent history of impotence not previously investigated. Bladder and bowel function were normal. He had no significant past medical history, and no history of neck or back pain.

Examination and initial investigations

The cranial nerves were normal. There was predominantly distal weakness, more marked in the legs, MRC grade 3/5. He had absent tendon reflexes, down going plantar responses, and "glove and stocking" sensory loss to pain, light touch, vibration, and joint position . . . [Full text of this article]







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Copyright © 2006 by the BMJ Publishing Group Ltd.