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A middle aged woman presents with progressiveweakness in thelegs, ascending numbness on the trunk, and urinaryretention.Within four days she has a paralysed right leg, severeleftleg weakness, and loss of position sense in the feet. Painsensationreduced to T4 right, T11 dermatome on the left, sparinglowersacral dermatomes. Over the previous eight years therehavebeen three episodes of optic neuritis, the most recenttwo weeksbefore this presentationthese had reduced acuityto justlight perception in the right eye. Her sagittal T2 MRIscanof the cervical and upper thoracic spinal cord is illustrated.