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ALS: pitfalls in the diagnosis

¹ Neurologist, Beaver Medical Group, Highland, CA, USA
² Assistant Clinical Professor of Neurosciences, Department of Neurology, University of California San Diego, San Diego, CA, USA

Correspondence to:
Correspondence to:
Dr N P Desai
Department of Neurology, University of California San Diego, 9350 Campus Point Drive, La Jolla, CA 92093-0973, USA; npdesai@ucsd.edu

The first 150 words of the full text of this article appear below.

A previously healthy man in his sixties presented with a 10-year history of progressive symmetrical and proximal lower extremity weakness, muscle atrophy, and fasciculations without any pain or sensory symptoms, which had spread gradually to his proximal upper extremities. Recently he had also noted weakness in his left hand causing difficulty clipping his nails. In addition, he had a five-year history of slurred speech without any difficulty swallowing. He had had mild dyspnoea on exertion and moderate low back pain for years. He denied any muscle pains or cramps, or any cognitive, cranial, bowel or bladder symptoms. He had been diagnosed with progressive muscular atrophy two years previously and came to our clinic for continuity of care. He had borderline diabetes and hypertension, but was otherwise well. There was no family history of any neuromuscular disorder, and he did not smoke or drink alcohol.

The abnormal neurological signs included mild . . . [Full text of this article]

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Charles Warlow
Practical Neurology 2007 7: 69. [Extract] [Full Text] [PDF]