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Diabetic neuropathies

Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA

Correspondence to:
Correspondence to:
Dr A A Little
Clinical Director, Peripheral Neuropathy Center, University of Michigan Department of Neurology, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA; alitt@umich.edu

The first 150 words of the full text of this article appear below.

Neuropathy is one of the many complications of both type 1 and type 2 diabetes mellitus, along with retinopathy, nephropathy, coronary heart disease, peripheral vascular disease, stroke and other sequelae of macrovascular and microvascular pathology. The financial toll exerted by diabetes in the US alone is over $132 billion per annum, half of which is attributable to diabetic complications.¹

• Type 1 diabetes accounts for about 10% of the diabetic population; it often, but not always, presents in childhood or adolescence and is an autoimmune disease with destruction of the pancreatic beta cells that manufacture insulin.
  
• Type 2 diabetes, accounting for about 90% of diabetic cases, is common in most high-income countries and is increasing in prevalence.² For example, in the population-based Framingham Heart Study, the eight-year incidence in middle-aged adults doubled (in women from 2.0% to 3.7%, in men from 2.7% to 5.8%) from the 1970s through the 1990s, mostly . . . [Full text of this article]

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Charles Warlow
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