Practical Neurology

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Practical Neurology 2007;7:145-157; doi:10.1136/jnnp.2007.120063
Copyright © 2007 by the BMJ Publishing Group Ltd.
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Complex? Regional? Pain? Syndrome?

G D Schott

Consultant Neurologist, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK; geoffrey.schott@uclh.nhs.uk

The first 150 words of the full text of this article appear below.

The story of complex regional pain syndrome (CRPS) begins in 1864. During the American Civil War, the father of American neurology, Silas Weir Mitchell (fig 1Go), together with Morehouse and Keen, observed that soldiers sustaining major nerve injuries affecting their limbs sometimes experienced long-lasting pain that was burning in quality, and "so frequent and terrible as to demand from us the fullest description".1 Soon afterwards he termed the condition causalgia (Greek: kausos (heat) + algos (pain)). Mitchell’s account, in which he graphically describes many of the associated features shown in table 1Go, is one of the classics of neurology.


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  		Figure 1 Silas Weir Mitchell (1829–1914).

 

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  		Table 1 The various accompanying features seen in complex regional pain syndrome
 
At the beginning of the 20th century, Paul Sudeck made two important contributions.2 First, only five years after x rays had been discovered, he identified the localised bone atrophy ("Knochenatrophie") that can develop in the . . . [Full text of this article]


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