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Neuroimaging |
Honorary Research Fellow & Specialist Registrar in Neurology, Dementia Research Centre, Institute of Neurology, University College London, 811 Queen Square, London WC1N 3BG, UK; jschott@dementia.ion.ucl.ac.uk
| The first 150 words of the full text of this article appear below. |
The advent of non-invasive imaging has revolutionised in vivo diagnosis of many medical conditions. This is exemplified by the use of MR scanning of the brain in the investigation of neurological disease. Historically, many pathological conditions have been described in terms of their resemblance to foods, for example: sago spleen (amyloid deposition); nutmeg liver (chronic venous congestion); anchovy sauce liver (amoebic abscess); popcorn cell (Hodgkins disease); and strawberry gall bladder (cholesterolosis).1 The imaging revolution appears however to have heralded a metaphorical change, with an increasing tendency to describe scan appearances in terms of animate objects. There is now it seems a "neurological MRI menagerie", and it is expanding.
PROGRESSIVE SUPRANUCLEAR PALSY: THE HUMMINGBIRD OR PENGUIN SIGN, AND THE MICKEY MOUSE SIGN
Progressive supranuclear palsy (PSP), an atypical parkinsonian syndrome previously known as the Steele-Richardson-Olszewski syndrome, has a prevalence of
5/100,000. Characteristic features include the insidious development in middle age of early postural instability leading to falls; a vertical supranuclear gaze palsy; axial rigidity;
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Practical Neurology 2007 7: 139.
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