Clinicopathological conference
Clear cell carcinoma of the kidney in a young man with neurological complications
1 Department of Neurology, University Hospital of Wales, Cardiff, UK
2 Department of Neurology, Gloucester Royal Hospital, Gloucester, Gloucestershire, UK
3 Department of Pathology, University Hospital of Wales, Cardiff, UK
Correspondence to:
Correspondence to:
Dr T Hughes
Consultant Neurologist, Department of Neurology, University Hospital of Wales, Heath Park, Cardiff CF14 4XN, UK; Tom.hughes@cardiffandvale.wales.nhs.uk
| The first 150 words of the full text of this article appear below. |
A 43-year-old man presented in April 2004 with a six-week history of a runny nose and a "cold", and for three weeks he had also been feeling generally unwell with mild vertigo, tinnitus and unsteadiness; the latter symptoms had worsened over a week but had not progressed for two weeks. On examination his blood pressure was 120/70, he was afebrile, and there was no meningism. He was orientated, and told his own story. Fundoscopy was normal. There was fine gaze-evoked bilateral horizontal nystagmus and obvious ataxia of his upper and lower limbs and gait. General medical examination, including the testicles and skin, was normal.
He was extensively investigated and the following tests were normal or negative: full blood count, urea and electrolytes, liver function (alkaline phosphatase 52 IU/l (30–115), aspartate transaminase 31 IU/l (5–45)), thyroid function, ANCA, anti-dsDNA antibodies, C-reactive protein, vitamin B12 and folate, calcium, chest x ray, 12-lead
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Practical Neurology 2007 7: 279.
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