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EDITOR’S CHOICE

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Although I am not a card-carrying epidemiologist it has not been difficult for me to realise that there is something terribly frustrating about the neurological complications of coeliac disease literature. No wonder such strong emotions are aroused—the protagonists are arguing over flawed and contradictory data. Gerald Grossman from Cleveland, Ohio, sets out all the methodological problems for us on page 77, warns us about the conflict between serological and histological diagnosis (just what is the diagnostic gold standard for coeliac disease supposed to be?), gives us his best bet of a bottom line and what to do with the next patient, and makes the very reasonable suggestion that far better studies need to be done. Maybe more neurologists should get some qualifications in epidemiology, or at the very least work with epidemiologists, rather than producing any more flawed studies. After all we are dealing here with potentially curable neurological problems, . . . [Full text of this article]