Article Text

PDF
Neurolupus
  1. Fady G Joseph1,
  2. Neil J Scolding2
  1. 1Consultant Neurologist, Neville Hall Hospital, Abergavenny and the Royal Gwent Hospital, Newport, UK
  2. 2Burden Professor of Clinical Neurosciences, Department of Neurology, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, UK
  1. Professor N Scolding, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, UK; n.j.scolding{at}bristol.ac.uk

Abstract

Systemic lupus erythematosus (SLE) is not an uncommon condition. Most neurologists are well aware that it can cause a wide range of neurological complications, and SLE almost invariably appears on ‘differential diagnosis’ lists in cases of clinical uncertainty. However, the precise nature of the manifestations of SLE in the central and peripheral nervous systems is perhaps less widely understood, and misperceptions about phenomenology and treatment are common. Here we survey some of the main primary neurological complications of SLE—‘neurolupus’—while acknowledging that secondary problems, either iatrogenic or relating to other consequences of SLE (eg, hypertensive CNS disease, for example, secondary to renal lupus) are neither less serious nor less treatable.

Statistics from Altmetric.com

Footnotes

  • Competing interests None

  • Provenance Commissioned; externally peer reviewed.

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.