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The opsoclonus–myoclonus syndrome
  1. Jitendra Kumar Sahu1,
  2. Kameshwar Prasad2
  1. 1Senior Research Associate, Department of Neurology, All India Institute of Medical Sciences, New Delhi, India
  2. 2Professor, Department of Neurology, All India Institute of Medical Sciences, New Delhi, India
  1. Correspondence to Dr K Prasad, Department of Neurology, All India Institute of Medical Sciences, New Delhi, India; kp0704{at}gmail.com

Abstract

The opsoclonus–myoclonus syndrome is a rare and distinct neurological disorder characterised by rapid multidirectional conjugate eye movements (opsoclonus), myoclonus and ataxia, along with behavioural changes in adults and irritability in children. Sometimes it is due to a self-limiting presumed para-infectious brainstem encephalitis but it may also represent a non-metastatic manifestation of neuroblastoma in children and small cell carcinoma of the lung in adults. In this article, we will describe the clinical features, diagnosis, pathogenesis and management.

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Footnotes

  • Competing interests None.

  • Provenance and peer Commissioned; externally peer reviewed.

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