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Carphology by A Fo Ben

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Drugs good, surgery better

Early surgical therapy for drug-resistant temporal lobe epilepsy appears to be superior to drug treatment alone. A North American trial was halted early: 38 people were randomised, when the target was 200. At this stage, surgery was clearly superior at maintaining freedom from seizure at 2 years (11/15 with surgery vs 0/23 without, p<0.001). However, care must be taken when looking at secondary endpoints. Controversially, the data and safety monitoring board (who halted the trial) blamed slow recruitment—but they also had access to unblinded outcome data.

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Susac's gift

Dr John Susac passed away earlier this year at the age of 71. To his colleagues he will be remembered for his intellect and his compassion; to the world he will be remembered for his eponymous syndrome; and to a select few he will be remembered for his generosity. …

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