Article Text

PDF
Sudden proximal paraparesis secondary to statin myositis
  1. Julien Lagarde1,
  2. Corina Cret1,
  3. Dalia Dimitri2,
  4. Frédéric Klapczynski1,
  5. Alain Améri1
  1. 1Department of Neurology, Centre hospitalier de Meaux, Meaux cedex, France
  2. 2Centre de référence des maladies neuro-musculaires Garches-Necker-Mondor-Hendaye, AP-HP, Consultation des pathologies neuro-musculaires, Service d'histologie, INSERM U841, CHU Henri Mondor, Créteil, France
  1. Correspondence to Dr Corina Cret, Department of Neurology, Centre hospitalier de Meaux, 6-8 rue Saint-Fiacre, FR-77104 Meaux cedex, France; c-cret{at}ch-meaux.fr

Statistics from Altmetric.com

Introduction

Myotoxicity due to statin medication is a well-known entity. Statin myopathies usually evolve either subacutely or chronically.1 They are classically diffuse, affecting all four limbs mainly proximally; focal myositis is rare in this setting.2 ,3 We report an atypical case of statin myopathy predominantly involving the quadriceps muscles with an unexpectedly abrupt onset.

Case report

A 75-year-old man presented with sudden onset of bilateral proximal lower limb weakness. On trying to stand up after finishing dinner, he had fallen backwards without losing consciousness. He had great difficulty getting up again and lay on the floor for several hours before being able to call for help. He had never previously experienced muscle pain or weakness and had not performed any unusual exercise in the preceding days or hours. He had a history of hypertension, diabetes mellitus, myocardial infarction and coronary bypass surgery. He took atenolol, metformin, aspirin and rosuvastatin. He did not …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Editors' choice
    Phil Smith Geraint Fuller