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  1. Phil E M Smith1,
  2. Geraint N Fuller2
  1. 1 Department of Neurology, University Hospital of Wales, Cardiff, UK
  2. 2 Gloucester Royal Hospital, Gloucester, UK
  1. Correspondence to Dr Geraint N Fuller, Gloucester Royal Hospital, Gloucester GL1 3NN, UK; geraint.fuller{at}

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It seems incredible now, but in the late 1980s hospitals in areas with high rates of HIV infection were full of young men with AIDS, many with neurological complications. The HIV epidemic seemed set to spread and one could foresee the management of neurological complications of HIV becoming a large part of neurological practice. Fortunately, public health interventions and highly effective antiretroviral treatments have dramatically changed this. While HIV is still a mimic for many conditions and remains a diagnostic challenge its effect on other pathologies is rather less than one might expect – as illustrated in the case of leprosy reported by Clare Galtrey and colleagues (see page 135 ).

As the threat of HIV receded in …

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