Article Text

PDF

Low CSF Volume (Pressure) Headache
  1. Peter J Goadsby*,
  2. Christopher Boes*,
  3. Cathie LM Sudlow
  1. *Headache Group, Institute of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, Email: peter{at}ion.ucl.ac.uk;
  2. Mayo Clinic Department of Neurology, Rochester, MN, USA;
  3. Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK

    Abstract

    The syndrome of persistent low cerebrospinal fluid (CSF) volume (pressure) headache is an important diagnosis for neurologists and others not to miss, because it is a treatable cause of disabling headache. It forms part of the more general diagnostic rubric of New Daily Persistent Headache (NDPH), the key feature of which is a new headache that develops over one or just a few days, and then persists (Li & Rozen 2002). This presentation should trigger a consideration of the differential diagnosis of NDPH (Table 1), particularly of treatable causes for the syndrome. Low CSF volume (pressure) headache is a very good example of this clinical phenotype.

    PATHOPHYSIOLOGY

    While the concept of low CSF volume (pressure) headache may seem simple enough on the surface, it has some complexities. The pain is generally considered to be due to traction on pain-producing intracranial structures – large vessels, large venous sinuses and dura mater. Indeed

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.