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Temporal lobe abnormalities in neurosyphilis
  1. Andrea Mignarri1,
  2. Umberto Arrigucci2,
  3. Piero Coleschi3,
  4. Roberta Bilenchi4,
  5. Antonio Federico1,
  6. Maria Teresa Dotti1
  1. 1Unit of Neurology and Neurometabolic Disorders, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy
  2. 2Unit of Diagnostic and Therapeutic Neuroradiology, Azienda Ospedaliera Siena, Siena, Italy
  3. 3Unit of Neurology, Ospedale San Donato Arezzo, Arezzo, Italy
  4. 4Unit of Dermatology, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy
  1. Correspondence to Professor Maria Teresa Dotti, Unit of Neurology and Neurometabolic Disorders, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena 53100, Italy; dotti{at}unisi.it

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A 28-year-old woman presented with a 5-month history of cognitive and behavioural disturbances. Her past history was unremarkable, and she had no family history of neurological disorders. On examination, she showed temporospatial disorientation, ideomotor apraxia, gait ataxia, dysarthria, anisocoria and reduced pupillary light responses. Routine blood tests were normal. MR scan of brain showed T2/FLAIR temporal hyperintensities (figure 1). Cerebrospinal fluid (CSF) analysis showed …

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