Article Text

Neurological complications of renal dialysis and transplantation
  1. Kushan Karunaratne1,
  2. David Taube2,
  3. Nofal Khalil3,
  4. Richard Perry1,4,
  5. Paresh A Malhotra1,4
  1. 1Department of Neurology, Imperial College Healthcare NHS Trust, London, UK
  2. 2Department of Renal and Transplantation Medicine, West London Renal and Transplant Centre, Imperial College Kidney and Transplant Institute, London, UK
  3. 3Department of Neurophysiology, Imperial College Healthcare NHS Trust, London, UK
  4. 4Division of Brain Sciences, Imperial College London, London, UK
  1. Correspondence to Dr Paresh A Malhotra, Department of Neurology, Hammersmith Hospital, London, W12 OHS, UK; p.malhotra{at}


Neurological complications from renal replacement therapy contribute significantly to morbidity and mortality in patients with renal failure. Such complications can affect either the central or peripheral nervous systems. Most neurological disturbances associated with the uraemic state do not respond fully to renal replacement therapy. There are also complications specifically associated with dialysis and transplantation. A multidisciplinary approach, involving both nephrologists and neurologists, is critical for the diagnosis and effective management of these disorders.

  • haemodialysis
  • dialysis
  • renal transplant
  • neurological complications

Statistics from


  • Twitter @pareshmalhotra

  • Contributors KK wrote the first draft. DT, RP and NK contributed in the writing of the paper. PM contributed to writing and final approval of the paper.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; externally peer reviewed. This paper was reviewed by Neil Anderson, Auckland, New Zealand.

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.