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Transient cortical blindness following gadolinium contrast
  1. Dimitri Renard,
  2. Constance Chevalier,
  3. Anne Wacongne
  1. Department of Neurology, Nîmes University Hospital, Nîmes, France
  1. Correspondence to Dr Dimitri Renard; dimitrirenard{at}

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A 49-year-old man developed transient (48 hours) cortical blindness following diagnostic cerebral angiography (normal) that had been performed to investigate a cerebellar haemorrhage from 6 months before. His blood pressure was normal during the diagnostic angiography. Gadolinium-enhanced MR scan of brain 2 hours after angiography showed restricted diffusion in the occipital cortex, predominantly left sided, with normal fluid attenuation inversion recovery (FLAIR) sequences (figure 1). Seven hours later, diffusion-weighted imaging was unchanged but FLAIR showed bilateral subarachnoid occipital hyperintensities which were not visible on other sequences, including T2*-weighted imaging (figure 1). Six days later, repeat imaging was completely normal (figure 1).

Figure 1

Initial gadolinium-injected MR scan of brain showing restricted diffusion predominantly in the left occipital cortex (A, diffusion-weighted imaging; B, apparent diffusion coefficient), with normal fluid attenuation inversion recovery (FLAIR) imaging (C). MR scan of …

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