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51-year old man with tingling, burning and progressive limb weakness
  1. Anu Gupta1,
  2. Pappula Santhosh Kumar1,
  3. Vinod Puri2,
  4. Ravindra Kumar Saran3,
  5. Poonam Narang4,
  6. Debashish Chowdhury1
  1. 1Department of Neurology, Govind Ballabh Pant Institute of Post Graduate Medical Education and Research (GIPMER), New Delhi, India
  2. 2Department of Neurology, Max Super Speciality Hospital, New Delhi, India
  3. 3Department of Pathology, Govind Ballabh Pant Institute of Post Graduate Medical Education and Research (GIPMER), New Delhi, India
  4. 4Department of Radiology, Govind Ballabh Pant Institute of Post Graduate Medical Education And Research (GIPMER), New Delhi, India
  1. Correspondence to Dr Anu Gupta, Department of Neurology, GIPMER, New Delhi 110002, India; doctoranugupta1{at}gmail.com

Abstract

Peripheral neuropathy is a common reason for referral to neurology. Chronic acquired demyelinating neuropathies are an important and varied group with overlapping presentations, and may have an immune-mediated cause. Their correct diagnosis is important as they respond to different treatments; timely intervention can prevent irreversible axonal degeneration. We present a case that highlights the approach to an adult presenting with a chronic demyelinating neuropathy.

  • POEMS syndrome
  • Polyneuropathy
  • CIDP
  • plasma cell dyscrasia
  • castleman’s disease

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Footnotes

  • Contributors AG, VP and DC contributed to the concept and design of the article. AG, PSK, RKS and PN contributed to the data acquisition, drafting of the text and/or the figures. All authors contributed to critical review and final approval of the manuscript.

  • Competing interests None declared.

  • Patient consent Next of kin consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed by Michael Lunn, London, UK.

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