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51-year old man with tingling, burning and progressive limb weakness

Abstract

Peripheral neuropathy is a common reason for referral to neurology. Chronic acquired demyelinating neuropathies are an important and varied group with overlapping presentations, and may have an immune-mediated cause. Their correct diagnosis is important as they respond to different treatments; timely intervention can prevent irreversible axonal degeneration. We present a case that highlights the approach to an adult presenting with a chronic demyelinating neuropathy.

  • POEMS syndrome
  • Polyneuropathy
  • CIDP
  • plasma cell dyscrasia
  • castleman’s disease

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