PT  - JOURNAL ARTICLE
AU  - Shin C Beh
AU  - Brinda Muthusamy
AU  - Peter Calabresi
AU  - John Hart
AU  - David Zee
AU  - Vivek Patel
AU  - Elliot Frohman
TI  - Hiding in plain sight: a closer look at posterior cortical atrophy
AID  - 10.1136/practneurol-2014-000883
DP  - 2015 Feb 01
TA  - Practical Neurology
PG  - 5--13
VI  - 15
IP  - 1
4099  - http://pn.bmj.com/content/15/1/5.short
4100  - http://pn.bmj.com/content/15/1/5.full
SO  - Pract Neurol2015 Feb 01; 15
AB  - Posterior cortical atrophy (PCA) is a neurodegenerative syndrome dominated by deterioration of higher visual function (particularly visuospatial and visuoperceptual abilities). It is most commonly due to Alzheimer's disease pathology, but may also be caused by dementia with Lewy bodies, corticobasal degeneration or Creutzfeldt-Jakob disease. Patients often present to optometrists, ophthalmologists and/or neurologists with non-specific visual complaints, and unless clinicians seek the specific symptoms and signs of PCA (beyond that of the ‘standard’ neurological examination), this infrequent disorder is easily missed, delaying its diagnosis and treatment. We review the clinical features of PCA, focusing on its visual manifestations, to help neurologists recognise this important syndrome.