RT Journal Article SR Electronic T1 Neurostimulation in the treatment of primary headaches JF Practical Neurology JO Pract Neurol FD BMJ Publishing Group Ltd SP 362 OP 375 DO 10.1136/practneurol-2015-001298 VO 16 IS 5 A1 Sarah Miller A1 Alex J Sinclair A1 Brendan Davies A1 Manjit Matharu YR 2016 UL http://pn.bmj.com/content/16/5/362.abstract AB There is increasing interest in using neurostimulation to treat headache disorders. There are now several non-invasive and invasive stimulation devices available with some open-label series and small controlled trial studies that support their use. Non-invasive stimulation options include supraorbital stimulation (Cefaly), vagus nerve stimulation (gammaCore) and single-pulse transcranial magnetic stimulation (SpringTMS). Invasive procedures include occipital nerve stimulation, sphenopalatine ganglion stimulation and ventral tegmental area deep brain stimulation. These stimulation devices may find a place in the treatment pathway of headache disorders. Here, we explore the basic principles of neurostimulation for headache and overview the available methods of neurostimulation.