RT Journal Article
SR Electronic
T1 Internuclear ophthalmoplegia
JF Practical Neurology
JO Pract Neurol
FD BMJ Publishing Group Ltd
SP 149
OP 153
DO 10.1136/practneurol-2016-001428
VO 17
IS 2
A1 Jonathan D Virgo
A1 Gordon T Plant
YR 2017
UL http://pn.bmj.com/content/17/2/149.abstract
AB A brainstem lesion of any type that involves the medial longitudinal fasciculus (MLF) can cause internuclear ophthalmoplegia (INO). This primarily affects conjugate horizontal gaze and classically manifests as impaired adduction ipsilateral to the lesion and abduction nystagmus contralateral to the lesion. Here, we describe the anatomy of the MLF and review the clinical features of INO. We also describe conjugate horizontal gaze palsy and some of the ‘INO-plus’ syndromes.