PT - JOURNAL ARTICLE AU - Vijayabala Jeevagan AU - Athula Dissanayake TI - Chorioretinitis: a potential clue to the early diagnosis of subacute sclerosing panencephalitis AID - 10.1136/practneurol-2017-001646 DP - 2017 May 16 TA - Practical Neurology PG - practneurol-2017-001646 4099 - http://pn.bmj.com/content/early/2017/05/16/practneurol-2017-001646.short 4100 - http://pn.bmj.com/content/early/2017/05/16/practneurol-2017-001646.full AB - We describe a 36-year-old man with subacute sclerosing panencephalitis (SSPE) presenting with chorioretinitis two years before onset of other neurological features. He had neither myoclonus nor the typical EEG features of SSPE. The diagnosis was confirmed in the appropriate clinical setting by detecting elevated measles antibody titres in cerebrospinal fluid and serum. Clinicians should consider SSPE among the differential diagnoses in chorioretinitis. This is particularly so if there is macular or perimacular involvement with concurrent involvement of the optic nerve in young patients, even without other characteristic neurological symptoms.