PT - JOURNAL ARTICLE AU - Brendan N Mclean AU - James Gulliver AU - Harry R Dalton TI - Hepatitis E virus and neurological disorders AID - 10.1136/practneurol-2016-001588 DP - 2017 Aug 01 TA - Practical Neurology PG - 282--288 VI - 17 IP - 4 4099 - http://pn.bmj.com/content/17/4/282.short 4100 - http://pn.bmj.com/content/17/4/282.full SO - Pract Neurol2017 Aug 01; 17 AB - Hepatitis E is the most common cause of hepatitis worldwide. While originally considered a disease of developing countries, it is increasingly recognised in developed countries, probably related to contaminated pork meat, and where infection is often asymptomatic. However, several non-liver manifestations have become apparent, the most important of which are neurological, including Guillain-Barré syndrome (acute inflammatory demyelinating polyradiculoneuropathy (AIDP)), neuralgic amyotrophy and meningoencephalitis. We recommend testing all patients with AIDP and neuralgic amyotrophy for hepatitis E and consider testing any patient with an unexplained neurological illness and abnormal liver function tests for the virus.