I Rapidly progressive dementia | II (A) Myoclonus |
(B) Visual or cerebellar problems | |
(C) Pyramidal or extrapyramidal features | |
(D) Akinetic mutism | |
III Typical EEG | 1.0 Definite: Neuropathologically/immunocytochemically confirmed |
2.0 Probable: I + 2 of II + III or I + 2 of II + positive 14-3-3 CSF protein | |
3.0 Possible: I + 2 of II + duration <2 years | |
4.1 Unclear diagnosis, not meeting sCJD criteria | |
4.2 Clinical diagnosis not sCJD |