Prevalence of non-motor symptoms from published studies using NMSQuest1 6–8 41–44
| Non-motor symptoms | Mean (%) | Range (%) |
|---|---|---|
| Cognitive | ||
| Memory | 45.8 | 37.9–62.5 |
| Concentration | 38.7 | 29.6–50.0 |
| Depression | ||
| Sadness | 42.5 | 22.5–56.0 |
| Anxiety | 43.4 | 30.7–55.8 |
| Sleep | ||
| Excessive daytime somnolence | 30.5 | 21.2–37.1 |
| Insomnia | 40.9 | 17.6–52.5 |
| REM sleep behaviour disorder | 34.2 | 29.6–38.7 |
| Restless legs syndrome | 35.8 | 27.7–41.1 |
| Fatigue | 41.5 | 31.1–58.1 |
| Pain | 31.1 | 18.2–45.9 |
| Gastrointestinal | ||
| Swallowing | 25.4 | 16.1–30.3 |
| Constipation | 46.5 | 27.5–71.7 |
| Urinary | ||
| Urgency | 53.4 | 35–61 |
| Nocturia | 53.8 | 26.4–66.7 |
| Global comparison | ||
| NMSQ-PD | 8.3 | 4–19 |
| NMSQ-C | 3.5 | 2–12 |
Data taken from studies by Chaudhuri et al;1 Chaudhuri et al;6 Mollenhauer et al;7 Khoo et al;8 Martinez-Martin et al;41 Barone et al;42 Crosiers et al;43 Chen et al;44 and expresses mean values of non-motor symptoms.
PD, Parkinson's disease; NMSQ-PD, Non-Motor Symptoms Questionnaire in PD patients; NMSQ-C, NMSQ—in controls.