Table 3

Effect of mechanical thrombectomy compared with best medical therapy on good functional outcome (modified Rankin Score≤2* at 90 days)

TrialMechanical thrombectomyBest medical therapyAdjusted OR (95% CI)
p value
MR CLEAN3576 (32.6)51 (19.1)2.16 (1.39–3.38)
REVASCAT3645 (43.7)29 (28.2)2.1 (1.1–4.0)
EXTEND 1A3725 (71)14 (40)4.2 (1.4–12) p=0.01
SWIFT-prime3859 (60)33 (35)1.70 (1.23–2.33) p<0.001
ESCAPE3987 (53.0)43 (29.3)1.7 (1.3–2.2)
THRACE401065385 (42)1.55 (1.05–2.30) p=0.028†
THERAPY41193814301.4 (0.60–3.3) p=0.55
PISTE4217 (57)10354.92 (1.23–19.69)p=0.021‡
EASI4320 (50)§14 (38)p=0.36

  • Figures are number of patients (%).

  • *This corresponds to slight or no residual disability as a result of the stroke.

  • †Value at 30 days.

  • ‡Per protocol population analysis.

  • §19/35 anterior circulation, 1/5 posterior circulation.

  • ¶14/32 anterior circulation, 0/5 posterior circulation.

  • OR = odds ratio.