Thunderclap headache (TCH) is head pain that begins suddenly and is severe at onset.
TCH might be the first sign of subarachnoid haemorrhage, unruptured intracranial …

Background Health-related quality of life (HRQoL) is emerging as an important element of
clinical research in primary headache disorders, allowing a measure of the impact of …

Trigeminal neuralgia (TN) is a highly disabling disorder characterised by very severe, brief
and electric shock like recurrent episodes of facial pain. New diagnostic criteria, which …

Electrical stimulation of primary sensory afferents is known to have an antinociceptive effect.
Animal and functional imaging studies suggest a role for supraspinal structures in this …

Introduction Galcanezumab is a humanized monoclonal antibody binding calcitonin gene-
related peptide, used for migraine prevention. Methods A global, double-blind, 6-month …

Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and
tearing (SUNCT) and short-lasting unilateral neuralgiform headache attacks with cranial …

Objective.—To determine the brain structures involved in mediating the pain of hemicrania
continua using positron emission tomography. Background.—Hemicrania continua is a …

Objective Paroxysmal hemicrania (PH) is a severe, strictly unilateral headache that lasts 2 to
30 minutes, occurs more than five times daily, is associated with trigeminal autonomic …

Importance Spontaneous intracranial hypotension (SIH) is a highly disabling but often
misdiagnosed disorder. The best management options for patients with SIH are still …

Cluster headache is a strictly unilateral headache that occurs in association with cranial
autonomic features. We report a patient with a trigeminal nerve section who continued to …