Cell-based therapeutic strategies for multiple sclerosis

NJ Scolding, M Pasquini, SC Reingold, JA Cohen - Brain, 2017 - academic.oup.com
The availability of multiple disease-modifying medications with regulatory approval to treat
multiple sclerosis illustrates the substantial progress made in therapy of the disease …

Central nervous system sarcoidosis—diagnosis and management

JP Zajicek, NJ Scolding, O Foster, M Rovaris… - Qjm, 1999 - academic.oup.com
A series of 68 patients with neurosarcoidosis is reported, with particular emphasis on clinical
aspects, diagnosis and treatment. A classification system based on clinical diagnostic …

Primary progressive multiple sclerosis: progress and challenges

CM Rice, D Cottrell, A Wilkins… - Journal of Neurology …, 2013 - jnnp.bmj.com
Primary progressive multiple sclerosis (MS) has long been recognised as presenting great
difficulties to our management of what is increasingly a treatable neurological disease. Here …

Sarcoidosis of the nervous system

FG Joseph, NJ Scolding - Practical Neurology, 2007 - pn.bmj.com
Although sarcoidosis is rarely confined to the nervous system, any neurological features that
do occur frequently happen early in the course of the disease. The most common …

Aβ-related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy

NJ Scolding, F Joseph, PA Kirby, I Mazanti, F Gray… - Brain, 2005 - academic.oup.com
Idiopathic or primary angiitis of the CNS (PACNS) and cerebral amyloid angiopathy (CAA)
are unusual vasculopathies generally regarded as unrelated disorders. A few case reports …

Neurosarcoidosis: a study of 30 new cases

FG Joseph, NJ Scolding - Journal of Neurology, Neurosurgery & …, 2009 - jnnp.bmj.com
Methods: The frequency, nature, relationship to systemic features, value of investigation
findings and outcomes for a cohort of patients with neurosarcoidosis (NS) were studied by …

Vesicular removal by oligodendrocytes of membrane attack complexes formed by activated complement

NJ Scolding, BP Morgan, WAJ Houston, C Linington… - Nature, 1989 - nature.com
OLIGODENDROCYTES synthesize myelin in the central nervous system and maintain it in
lamellar sheaths around axons. Techniques for studying oligodendrocyte development in …

CNS lupus: a study of 41 patients

FG Joseph, GA Lammie, NJ Scolding - Neurology, 2007 - AAN Enterprises
Background: CNS lupus is a serious but potentially treatable illness, which, though long
recognized, may still present very difficult diagnostic challenges. We believed that further …

CSF oligoclonal band status informs prognosis in multiple sclerosis: a case control study of 100 patients

FG Joseph, CL Hirst, TP Pickersgill… - Journal of Neurology …, 2009 - jnnp.bmj.com
Objective: Oligoclonal band (OCB) negative multiple sclerosis (MS) is well recognised but
uncommon, studied in only a few usually small case series. These reached differing …

Interactions between oligodendrocytes and microglia: a major role for complement and tumour necrosis factor in oligodendrocyte adherence and killing

JP Zajicek, M Wing, NJ Scolding, DAS Compston - Brain, 1992 - academic.oup.com
Interactions between rat microglia and oligodendrocytes were examined in vitro in order to
characterize the stages of adherence, phagocytosis and cytotoxicity against …