The discovery of leptin, the product of the ob gene, has led to major developments in
understanding the regulation of energy balance. It is now recognised that leptin is produced …

Placental tissues from humans, rodents and farm animals contain leptin and its receptor.
Leptin produced by the human placenta has the same size, charge and immunoreactivity as …

More frequently hospital clinicians are reviewing images from MR studies of their patients
before seeking formal radiological opinion. This practice is driven by a multitude of factors …

Expression of the leptin receptor gene has been examined in mouse hypothalamus and
other brain regions by in situ hybridization. With a probe recognizing all the known splice …

Leptin is a 167-aa protein that is secreted from adipose tissue and is important in the
regulation of energy balance. It also functions in hematopoiesis and reproduction. To assess …

Leptin, the protein product of the adipose tissue-specific ob (obese) gene (1), reduces the
body weight, adiposity and food intake of obese ob/ob mice on peripheral or central injection …

Expression of leptin receptor splice variants, including the long form variant (Ob-Rb), has
been examined in murine peripheral tissues. RT-PCR indicates that the leptin receptor, Ob …

Iron content of the basal ganglia was investigated in 25 patients with idiopathic Parkinson's
disease and 14 matched healthy control subjects using a partially refocused interleaved …

Leptin expression in third trimester placenta (p) and leptin concentrations in umbilical cord
blood (cb) were investigated in normal pregnancies [n= 10 (p), 31 (cb)] and abnormal …

Background Acute demyelinating optic neuritis, a common feature of multiple sclerosis, can
damage vision through neurodegeneration in the optic nerve and in its fibres in the retina …