Metastatic bone disease develops as a result of the many interactions between tumour cells
and bone cells. This leads to disruption of normal bone metabolism, with the increased …

The skeleton is the most common organ to be affected by metastatic cancer and the site of
disease that produces the greatest morbidity. Skeletal morbidity includes pain that requires …

The skeleton is the most common organ to be affected by metastatic cancer, and tumors
arising from the breast, prostate, thyroid, lung, and kidney possess a special propensity to …

Background Rucaparib, a poly (ADP-ribose) polymerase inhibitor, has anticancer activity in
recurrent ovarian carcinoma harbouring a BRCA mutation or high percentage of genome …

Utilization of scientific terms in geology has several inherent problems, particularly when
contemplating both process and description. Ophiolite has had a particularly notorious …

Background Trastuzumab—a humanised monoclonal antibody against HER2—has been
shown to improve disease-free survival after chemotherapy in women with HER2-positive …

Background Dostarlimab is an immune-checkpoint inhibitor that targets the programmed cell
death 1 receptor. The combination of chemotherapy and immunotherapy may have …

ZINC is a free public resource for ligand discovery. The database contains over twenty
million commercially available molecules in biologically relevant representations that may …

Background There are limited data from retrospective studies regarding whether survival
outcomes after laparoscopic or robot-assisted radical hysterectomy (minimally invasive …

Background Radium-223 dichloride (radium-223), an alpha emitter, selectively targets bone
metastases with alpha particles. We assessed the efficacy and safety of radium-223 as …