This expert consensus statement reviews evidence on the effectiveness of drug and alcohol
self-help groups and presents potential implications for clinicians, treatment program …

The present paper reviews the literature on breakfast to consider reported associations
between breakfast and nutritional, physiological and biochemical variables. The contribution …

This article describes challenges and successes seen in the first four years of efforts the
state of Connecticut has made to reorient its behavioral health system to promoting recovery …

We mutated, by gene targeting, the endogenous hypoxanthine phosphorlbosyi transferase
(HPFlT) gene in mouse embryo-derived stem (ES) cells. A specialized construct of the …

Gene targeting—homologous recombination of DNA sequences residing in the
chromosome with newly introduced DNA sequences—in mouse embryo-derived stem cells …

THE int-1 proto-oncogene was first identified as a gene activated in virally induced mouse
mammary tumours1, 2. Expression studies, however, suggest that the normal function of this …

We corrected a defective gene residing in the chromosome of a mammalian cell by injecting
into the nucleus copies of the same gene carrying a different mutation. We determined how …

Axonal guidance and vascular patterning share several guidance cues, including proteins in
the netrin family. We demonstrate that netrins stimulate proliferation, migration, and tube …

The formation of the apical ectodermal ridge (AER) is critical for the distal outgrowth and
patterning of the vertebrate limb. Recent work in the chick has demonstrated that interplay …

Abstract Slit–Roundabout (Robo) signalling has a well-understood role in axon guidance,,,,.
Unlike in the nervous system, however, Slit-dependent activation of an endothelial-specific …