User profiles for "author:Thashi Chang"

Thashi Chang

Professor in Neurology, Department of Clinical Medicine, University of Colombo
Verified email at clinmed.cmb.ac.lk
Cited by 1143

[HTML][HTML] Serum IL-10 as a marker of severe dengue infection

GN Malavige, L Gomes, L Alles, T Chang… - BMC infectious …, 2013 - Springer
Background Several studies have shown that serum IL-10, IFNγ and MIF are elevated in
patients in severe dengue (SD) and could be used as potential biomarkers. We proceeded …

Prevalence of stroke and its risk factors in urban Sri Lanka: population-based study

T Chang, S Gajasinghe, C Arambepola - Stroke, 2015 - Am Heart Assoc
Background and Purpose—Stroke is a leading cause of disability and death worldwide. In
the absence of published population-based prevalence data, we investigated the …

[HTML][HTML] Evaluation of the WHO revised criteria for classification of clinical disease severity in acute adult dengue infection

SD Jayaratne, V Atukorale, L Gomes, T Chang… - BMC research …, 2012 - Springer
Background The WHO guidelines were revised recently to identify patients with severe
dengue (SD) early. We proceeded to determine the usefulness of the warning signs in the …

[HTML][HTML] Selected serum cytokines and nitric oxide as potential multi-marker biosignature panels for Parkinson disease of varying durations: a case-control study

D Rathnayake, T Chang, P Udagama - BMC neurology, 2019 - Springer
Background Dopaminergic neuronal loss begins years before motor symptoms appear in
Parkinson disease (PD). Thus, reliable biomarkers for early diagnosis and prognosis of PD …

[HTML][HTML] Hydrogen sulphide inhalational toxicity at a petroleum refinery in Sri Lanka: a case series of seven survivors following an industrial accident and a brief review …

MC Shivanthan, H Perera, S Jayasinghe… - Journal of occupational …, 2013 - Springer
This case series details clinical observations in 7 survivors of accidental hydrogen sulphide
inhalation toxicity at a petroleum refinery in Sri Lanka. One survivor developed status …

Neuronal surface and glutamic acid decarboxylase autoantibodies in nonparaneoplastic stiff person syndrome

T Chang, H Alexopoulos, M McMenamin… - JAMA …, 2013 - jamanetwork.com
Importance High titers of autoantibodies to glutamic acid decarboxylase (GAD) are well
documented in association with stiff person syndrome (SPS). Glutamic acid decarboxylase is …

Long-term health complications following snake envenoming

S Jayawardana, C Arambepola, T Chang… - Journal of …, 2018 - Taylor & Francis
Background Snakebite is an important public health problem in tropical regions of the world.
Although devastating effects of envenoming such as kidney failure, tissue necrosis, bleeding …

[HTML][HTML] Miller Fisher syndrome developing as a parainfectious manifestation of dengue fever: a case report and review of the literature

NL de Silva, P Weeratunga, T Umapathi… - Journal of Medical Case …, 2019 - Springer
Background Although dengue viral infections have emerged as one of the most important
mosquito-borne diseases, neurological manifestations of dengue infections are uncommon …

[HTML][HTML] Chronic musculoskeletal disabilities following snake envenoming in Sri Lanka: a population-based study

S Jayawardana, A Gnanathasan… - PLoS neglected …, 2016 - journals.plos.org
Background Snakebite is a major public health problem in agricultural communities in the
tropics leading to acute local and systemic impairments with resultant disabilities. Snakebite …

[HTML][HTML] Effective treatment of osmotic demyelination syndrome with plasmapheresis: a case report and review of the literature

M Wijayabandara, S Appuhamy… - Journal of Medical Case …, 2021 - Springer
Background Treatment options for chronic osmotic demyelination syndrome are limited to
case reports and only a very few show complete recovery. We report a case of complete …