Article Text

Essential thrombocythaemia and its neurological complications
  1. Thomas D Miller1,
  2. Mira H Farquharson2
  1. 1Core Medical Trainee, Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
  2. 2Consultant Haematologist, Department of Haematology, Western General Hospital, Edinburgh, UK
  1. Correspondence to Dr M H Farquharson, Department of Haematology, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK; mira.farquharson{at}


Essential thrombocythaemia is one of the chronic myeloproliferative neoplasms and is characterised by a sustained platelet count ≥450 × 109/l. The clinical course is often indolent but a significant number of patients have thrombotic and haemorrhagic complications. A patient with neurological complications is described, and the pathogenesis and clinical features of this disease are reviewed, including its neurological sequelae and management, along with an outline for the investigation of patients with thrombocytosis.

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  • Competing interests None.

  • Patient consent Obtained.

  • Provenance and peer review Commissioned; externally peer reviewed.

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