Juvenile myoclonic epilepsy is one of the most common types of epilepsy seen in an adult epilepsy clinic. Most patients have a good prognosis, particularly when treated with valproate, but a significant minority are more difficult to treat. In this article, we will focus on a management strategy when the initial antiepileptic drug is unsuccessful and outline an approach that translates directly to the clinic.
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Competing interests AN and AGM have received honoraria and/or hospitality from the pharmaceutical companies that manufacture all of the drugs discussed in this article.
Provenance and peer review Commissioned; externally peer reviewed.