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PCP prophylaxis with use of corticosteroids by neurologists
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  • Published on:
    Re:What is the risk of PCP in patients with neurological disease?

    We thank Dr Lilleker for his comments. We agree that use of PCP prophylaxis must provide benefit that would outweigh any attendant risk. As suggested in our article, this risk is likely to vary depending on the dose and duration of steroid therapy, the co-administration of other biologicals and the systemic health of the patient. A patient with e.g., systemic vasculitis-associated mononeuritis multiplex who has also b...

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    Conflict of Interest:
    None declared.
  • Published on:
    What is the risk of PCP in patients with neurological disease?

    I thank the authors for highlighting this difficult topic with a very thought provoking article.

    In immunosuppressing a patient with neurological disease, as with anything a physician does to a patient, there are potential risks to take into account and to be weighed up against the proposed benefits. Indeed, this sort of "cost-benefit" analysis is a central tenant of decision making in much of life outside of me...

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    Conflict of Interest:
    None declared.