Article Text

Download PDFPDF
Rapid-onset flaccid paraplegia caused by multiple myeloma dumbbell tumour
  1. Curtis Osborne1,
  2. Simon Stallworthy2,
  3. Jane Evanson3,
  4. Richard Sylvester4,
  5. Alastair J Noyce5
  1. 1Acute Medicine at Charing Cross Hospital, London, UK
  2. 2Acute Medicine at Whipps Cross Hospital, Barts Health NHS Trust, London, UK
  3. 3Department of Neuroradiology, Barts Health NHS Trust, London, UK
  4. 4UCL Institute of Neurology, London, UK
  5. 5Reta Lila Weston Institute for Neurological Studies, UCL Institute of Neurology, London, UK
  1. Correspondence to Dr Alastair Noyce, Reta Lila Weston Institute for Neurological Studies, UCL Institute of Neurology, London WC1N 1PJ, UK; a.noyce{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Case report

A 43-year-old female Ghanaian office cleaner presented to the emergency department with a 2-day history of progressive, ascending lower limb weakness, with sensory disturbance and urinary retention. There were 2 weeks of non-specific, intermittent back pain, but she had been previously well. She was a lifelong non-smoker and did not drink alcohol. On examination, she had a left Horner's syndrome but the cranial nerves and upper limbs were otherwise normal. In the lower limbs, power was absent in all muscle groups, with areflexia and hypotonia. There was patchy sensory loss but no clear sensory level. Cardiovascular, respiratory and abdominal examinations were normal.

Initial laboratory results found microcytic …

View Full Text


  • Contributors CO, SS and AJN were responsible for drafting the report. JE and RS made critical revisions. All authors were involved in the clinical care of this patient.

  • Competing interests None.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed. This paper was reviewed by Jeremy Rees, London, UK.

Linked Articles

  • Editors' choice
    Phil Smith Geraint Fuller

Other content recommended for you