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Temporal lobe abnormalities in neurosyphilis
  1. Andrea Mignarri1,
  2. Umberto Arrigucci2,
  3. Piero Coleschi3,
  4. Roberta Bilenchi4,
  5. Antonio Federico1,
  6. Maria Teresa Dotti1
  1. 1Unit of Neurology and Neurometabolic Disorders, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy
  2. 2Unit of Diagnostic and Therapeutic Neuroradiology, Azienda Ospedaliera Siena, Siena, Italy
  3. 3Unit of Neurology, Ospedale San Donato Arezzo, Arezzo, Italy
  4. 4Unit of Dermatology, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy
  1. Correspondence to Professor Maria Teresa Dotti, Unit of Neurology and Neurometabolic Disorders, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena 53100, Italy; dotti{at}unisi.it

https://doi.org/10.1136/practneurol-2014-000927

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    A 28-year-old woman presented with a 5-month history of cognitive and behavioural disturbances. Her past history was unremarkable, and she had no family history of neurological disorders. On examination, she showed temporospatial disorientation, ideomotor apraxia, gait ataxia, dysarthria, anisocoria and reduced pupillary light responses. Routine blood tests were normal. MR scan of brain showed T2/FLAIR temporal hyperintensities (figure 1). Cerebrospinal fluid (CSF) analysis showed …

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    Footnotes

    • Contributors AM was the PI and lead writer. UA, PC, RB and AF acquired and analysed the data. MTD was the coordinator of the study. All authors helped plan the study, interpret data and critically revise successive drafts of the manuscript.

    • Funding None.

    • Competing interests None.

    • Patient consent Obtained.

    • Ethics approval Local ethic committee.

    • Provenance and peer review Not commissioned; externally peer reviewed. This paper was reviewed by Nick Davies, London, UK.

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      Practical Neurology 2014; 14 367-367 Published Online First: 12 Nov 2014. doi: 10.1136/practneurol-2014-001020