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Contributors All the authors had access to the data and a role in the writing of the manuscript. GS and JMH wrote the draft manuscript. KP provided the muscle biopsy text. DAW, BMM and PB contributed to the drafting of the manuscript.
Funding This work was funded in part by the International Centre for Genetic Engineering and Biotechnology (ICGEB) and the Lily and Ernst Hausmann Research Trust.
Competing interests None.
Patient consent Obtained.
Ethics approval University of Cape Town Health Sciences Research Ethics Committee.
Provenance and peer review Not commissioned; externally peer reviewed. This paper was reviewed by Jon Walters, Swansea, UK.
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