Statistics from Altmetric.com
A young woman presented with a 2-month history of progressive severe spastic paraparesis. An MR scan of spine showed a longitudinally-extensive myelopathy (figure 1). MR scan of the brain was normal. Cerebrospinal fluid showed elevated protein at 1.33 g/L, a normal white cell count, no malignant cells and normal glucose. An exhaustive biological blood screening was negative except for detection of antibodies targeting the M23 isoform on aquaporin-4 transfected cells.
Contributors DB and RD: study design, drafting and revising the manuscript. CD and JS: data collection, critical comments during manuscript revision. KM: data collection, drafting and revising the manuscript. OG and RM: critical comments during manuscript revision.
Competing interests None.
Provenance and peer review Not commissioned; externally peer reviewed. This paper was reviewed by Jackie Palace, Oxford, UK, and Seth Love, Bristol, UK.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.