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Stroke-like migraine attack after cranial radiation therapy: the SMART syndrome
  1. Sue Yin Lim1,
  2. Jonathan Brooke2,
  3. Robert Dineen3,
  4. Michael O'Donoghue1
  1. 1Department of Neurology, Queen's Medical Centre, Nottingham, UK
  2. 2Medical High Dependency Unit, Queen's Medical Centre, Nottingham, UK
  3. 3Department of Neuroradiology, Queen's Medical Centre, Nottingham, UK
  1. Correspondence to Dr Sue Yin Lim; Department of Neurology, Nottingham University Hospitals NHS Trust, D Floor, West Block, Queens Medical Centre, Derby Road, Nottingham NG7 2UH, UK; niyeus{at}


We describe a patient who experienced a prolonged episode of headache, drowsiness, seizure, unilateral weakness, delusion and hallucination due to a stroke-like migraine attack after cranial radiation therapy. Stroke-like migraine attack after radiation therapy (SMART) syndrome is a rare complication of therapeutic brain irradiation.

  • SMART syndrome
  • brain radiotherapy

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