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Psychogenic non-epileptic seizures in early Huntington's disease
  1. Filipe Brogueira Rodrigues,
  2. Edward J Wild
  1. Huntington's Disease Centre, Institute of Neurology, University College London, London, UK
  1. Correspondence to Dr Edward J Wild, Department of Neurodegenerative Disease, Huntington's Disease Centre, Institute of Neurology, University College London, London WC1N 3BG, UK; e.wild{at}


Huntington's disease (HD) is a neurodegenerative condition characterised by motor dysfunction with involuntary movements and loss of voluntary control, cognitive deterioration and psychiatric problems. We report a 51-year-old man with early HD who experienced stereotyped episodes of repetitive, purposeless complex movements and unresponsiveness. His neurological examination was compatible with HD as were all investigations. We diagnosed psychogenic non-epileptic seizures. While seizures are common in juvenile-onset HD, they are no more prevalent in adult-onset HD than in the general population. However, neuropsychiatric symptoms are common in HD and can involve a number of different complaints. Patients may experience dissociative attacks soon after manifesting a HD diagnosis. Such episodes can be managed with patient and carer education, cognitive behavioural therapy and anxiolytic selective serotonin reuptake inhibitors.

  • Huntington disease
  • pseudoseizures
  • case reports

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  • Contributors EJW was the guarantor. FBR and EJW conceptualised the study, interpreted the data, drafted and revised the manuscript for intellectual content.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed. This paper was reviewed by Markus Reuber, Sheffield, UK.

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