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Clinicopathological case: progressive cognitive decline with gait disturbance in a steel worker
  1. Fiona C Moreton1,
  2. Robert Brenner2,
  3. Jayam Lazarus3,
  4. Richard Davenport1
  1. 1Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK
  2. 2Royal Free NHS Foundation Trust, London, UK
  3. 3Northern Lincolnshire and Goole Hospitals NHS Foundation Trust, Lincolnshire, UK
  1. Correspondence to Dr Fiona Moreton, Department of Clinical Neurosciences, Western General Hospital, Edinburgh, EH4 2XU, UK; fmoreton{at}


A 57-year-old male steel plant worker presented with fatigue and altered liver function tests. Over the next two years, he developed cognitive decline, parkinsonism and seizures. This paper reports the clinicopathological conference at the 37th Edinburgh Advanced Neurology Course 2015 and outlines what we can learn from this case.

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  • This case was presented at the 37th Edinburgh Advanced Neurology Course 2015.

  • Contributors FM took primary responsibility for writing this article and undertook a literature review. RB provided critical appraisal of the case. RB, JL and RD contributed towards the writing and review of the article.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed. This paper was reviewed by Rhys Davies, Liverpool, UK.

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