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Chorioretinitis: a potential clue to the early diagnosis of subacute sclerosing panencephalitis
  1. Vijayabala Jeevagan1,2,
  2. Athula Dissanayake1
  1. 1 Teaching Hospital Karapitiya, Galle, Sri Lanka
  2. 2 National Hospital of Neurology and Neurosurgery, London, UK
  1. Correspondence to Dr Vijayabala Jeevagan, National Hospital of Neurology and Neurosurgery, 33, Queen Square, London WC1N 3BG, UK; jeevaganv{at}


We describe a 36-year-old man with subacute sclerosing panencephalitis (SSPE) presenting with chorioretinitis two years before onset of other neurological features. He had neither myoclonus nor the typical EEG features of SSPE. The diagnosis was confirmed in the appropriate clinical setting by detecting elevated measles antibody titres in cerebrospinal fluid and serum. Clinicians should consider SSPE among the differential diagnoses in chorioretinitis. This is particularly so if there is macular or perimacular involvement with concurrent involvement of the optic nerve in young patients, even without other characteristic neurological symptoms.

  • subacute sclerosing panencephalitis
  • chorioretinitis

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  • Contributors VJ wrote the initial manuscript. AD revised and corrected the paper. All the authors agreed on final manuscript.

  • Competing interests None declared.

  • Patient consent Obtained from next of kin.

  • Provenance and peer review Not commissioned; externally peer reviewed. This paper was reviewed by Mark Lawden, Leicester, UK.