Article Text
Abstract
We present a case of cerebellar dysfunction due to severe hypothyroidism induced by pembrolizumab, a member of the ‘immune checkpoint inhibitor’ class of cancer immunotherapies. Thyroxine replacement completely resolved his symptoms and signs. We also discuss the neurological immune-related complications of checkpoint inhibitors.
- neuroimmunology
- cerebellar ataxia
- neuroendocrinology
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Footnotes
Contributors AB drafted this case report. CM and AJC edited the report and contributed to the discussion.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed. This paper was reviewed by Marios Hadjivassiliou, Sheffield, UK.
Correction notice This article has been corrected since it was published Online First. The affiliations numbered 2 and 3 have been switched around.
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