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PDFCarphology
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Every cloud
What inspired mind could read about the devastation of the Zika epidemic—be aware of the congenital brain malformations and then think… ‘Do you know what, I think the virus may have health benefits when injected into brain tissue?’ Zika virus induces cell death and differentiation of neural precursor cells in the developing fetus. Could this property be harnessed to combat glioblastoma (GBM)? In a study, Zika preferentially killed GBM stem cells rather than differentiated tumour progeny or normal neuronal cells. GBM mice had longer survival when inoculated with Zika too. I suggest our local ethics board will struggle with this suggestion until further studies are published.
J Exp Med 2017;214(10):2843–2857.
Talking back control
During …
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