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Contributors EM: was responsible for project concept and design, acquisition of data, manuscript preparation, and critical revision of manuscript for intellectual content. JC, NC, JP and NEA: critically revised the manuscript for intellectual content and was involved in supervision of the project.
Funding This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed. This paper was reviewed by Jon Walters, Swansea, UK.