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Mild encephalitis with reversible splenial (MERS) lesion syndrome due to influenza B virus
  1. Geraldine Vanderschueren1,
  2. Katlijn Schotsmans1,
  3. Emke Maréchal1,2,
  4. Roeland Crols1,3
  1. 1Department of Neurology, ZNA Middelheim, Antwerp, Belgium
  2. 2Department of Neurology, Antwerp University Hospital (UZA), Edegem, Belgium
  3. 3Department of Neurology, ‘Heilige Familie’ Hospital, Antwerp, Belgium
  1. Correspondence to Dr Geraldine Vanderschueren, Department of Neurology, ZNA Middelheim, Antwerp 2020, Belgium; dinvds{at}


We describe a 16-year-old boy with mild encephalitis with reversible lesions in the white matter and splenium of corpus callosum as a complication of an influenza B virus infection. Although more common in Asiatic children, it can also occur in Caucasian children and adults. There are several possible causes, including metabolic disorders, hypertension and infection, and the prognosis is usually good, even without treatment.

  • mild encephalitis with reversible splenial lesions (mers)
  • reversible splenial lesion syndrome (resles)
  • influenza
  • mri

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  • Contributors GV wrote the manuscript. KS, EM and RC revised the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed. This paper was reviewed by Aaron Berkowitz, Boston, UK.

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