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A 25-year-old woman gave a 3-year history of worsening headaches related to posture. She had Marfan’s syndrome and a background of infrequent migraine.
She defined two types of headache:
A ‘high pressure’ headache invariably developed if she lay flat for more than a few minutes, and improved on sitting or standing. Typically, these headaches developed over 1–2 min and were generalised without migrainous features. There was no change in vision, but sometimes she heard whooshing noises. Leaning forward when seated or the Valsalva manoeuvre could trigger similar symptoms.
A different ‘non-high pressure’ generalised headache was often triggered by moving to standing from lying or sitting. These headaches also developed rapidly, sometimes over a few seconds and would often improve over a few minutes if she …
Contributors GP, ER-I, SB and MIL: data collection and drafting the manuscript. SB, MIL and BRW: data interpretation and editing the manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed by Alex Sinclair, Birmingham, UK.
Data sharing statement We are happy to share all data for this case.