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Synkinetic wrist extension in distinguishing cortical hand from radial nerve palsy
  1. Francesco Brigo1,2,
  2. Giammario Ragnedda2,
  3. Piera Canu2,
  4. Raffaele Nardone2,3
  1. 1 Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy
  2. 2 Division of Neurology, Franz Tappeiner Hospital, Merano, Italy
  3. 3 Department of Neurology, Christian Doppler Medical Centre, Paracelsus Medical University, Salzburg, Austria
  1. Correspondence to Dr Francesco Brigo, Department of Neurosciences, Biomedicine, and Movement Sciences, University of Verona, Verona, 37134, Italy; dr.francescobrigo{at}


We describe a patient with pseudoradial nerve palsy caused by acute ischaemic stroke (‘cortical hand’) to emphasise how preserved synkinetic wrist extension following fist closure can distinguish this from peripheral causes of wrist drop.

  • padial nerve palsy
  • pseudoradial nerve palsy
  • differential diagnosis
  • stroke

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  • Contributors FB described the sign and wrote the article. GR collected clinical data. Other authors critically revised the article for important intellectual content.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests FB has received speakers' honoraria from Eisai and PeerVoice, payment for consultancy from Eisai, and travel support from Eisai, ITALFARMACO and UCB Pharma.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed by Simon Rinaldi, Oxford, UK.

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